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Amino acid sequence and structure of AmpC β-lactamase: (A) enzyme sequence showing the peptic fragments that could be quantified reproducibly in the mass spectrum both with and without the aggregator rottlerin; (B) two orientations of the structure of AmpC β-lactamase indicating the location of the peptic fragments that were observed in the mass spectrum (fragments shown in purple, active site residues shown in yellow).(39)
