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. Author manuscript; available in PMC: 2009 Apr 2.
Published in final edited form as: Neuropsychopharmacology. 2008 Apr 16;33(13):3226–3236. doi: 10.1038/npp.2008.53

Figure 4.

Figure 4

Neurons in the retrosplenial cortex and CA1 subregion of the hippocampus of Tg + mice following chronic administration with 20 mg/kg (panel a and b) and 5 mg/kg (panel c and d). The neurons have a normal morphological appearance without cytoplasmic vacuoles in both the retrosplenial cortex (panel a and c) and CA1 of the hippocampus (panel b and d). However, a few dark stained cells in the retrosplenial cortex showed the feature of degeneration (panel a, arrows indicated). Bar in panel d also applies to a, b and c.