Figure 4. RvD1 stops neutrophil chemotaxis.
A) Neutrophils having polarized morphology during exposure to IL-8 gradient (- 1 min), quickly become rounded (+ 1 min) and were unable to regain their polarized morphology (+ 5 min) after exposure to RvD1.
B) Population analysis shows that normal neutrophil migration in an IL-8 gradient is immediately and effectively blocked after exposure to RvD1. Results represent the mean ± SEM, n=12.