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Proposed Chemical Mechanism for Saccharopine Dehydrogenase. I. the formed central complex E:NAD:saccharopine once NAD and saccharopine bind. II. Schiff base intermediate. III. carbinolamine intermediate. IV. protonated carbinolamine. V. the generated central complex E:NADH:α-Kg-Lys. VI. protonated lysine. With the exception of saccharopine, no stereochemistry is implied.
