TABLE 2.

Histomorphometric analysis of the thoracic vertebral body in the three strains.

	Fluoride Treatment (ppm)	Strain A/J	Strain SWR/J	Strain 129P3/J
% Bone Volume of Tissue Volume BV/TV	0	11.48 ± 2.86	19.83 ± 3.15	24.65 ± 8.66
	25	12.55 ± 3.11	18.36 ± 3.54	24.50 ± 4.50
	50	13.58 ± 2.64	20.46 ± 4.72	23.69 ± 6.93
	100	12.85 ± 1.62	15.44 ± 2.89	24.43 ± 2.97
% Mineralized Bone of Tissue Volume MdV/TV	0	11.47 ± 2.84	19.83 ± 3.15	24.62 ± 8.64
	25	12.54 ± 3.11	18.35 ± 3.53	24.49 ± 4.50
	50	13.58 ± 2.64	20.45 ± 4.72	23.64 ± 6.93
	100	12.81 ± 1.62	15.43 ± 2.89	24.27 ± 2.94
% Osteoid Volume of Bone Volume OV/BV	0	0.01 ± 0.01	0.01 ± 0.02	0.11 ± 0.07
	25	0.02 ± 0.03	0.05 ± 0.05	0.05 ± 0.03
	50	0.04 ± 0.04	0.03 ± 0.03	0.20 ± 0.07
	100	0.26 ± 0.05 **	0.07 ± 0.03	0.64 ± 0.32 ***
% Osteoid Surface(OS/BS)	0	0.09 ± 0.19	0.22 ± 0.39	2.51 ± 1.65
	25	0.32 ± 0.45	0.54 ± 0.69	1.04 ± 0.83
	50	0.67 ± 0.59	0.40 ± 0.25	4.05 ± 1.18
	100	4.10 ± 0.91 ***	1.20 ± 0.54 *	9.40 ± 3.48 ***
Osteoid Thickness (mcm) OTh	0	0.38 ± 0.52	0.68 ± 0.76	1.24 ± 0.28
	25	0.31 ± 0.49	0.90 ± 0.72	1.16 ± 0.13
	50	0.94 ± 0.66	0.95 ± 0.53	1.40 ± 0.12
	100	1.37 ± 0.10	1.38 ± 0.25	1.61 ± 0.27 **

Data are presented as means ± SD.

A p value < 0.001 is noted as ***. A 0.001<p<0.05 is noted as ** and a 0.05<p< 0.1 is noted as *.

No significant statistical differences were noted for the BV/TV and mdV/TV, but there were significant differences in osteoid formation in the three strains.