Table 4.
Average weekly doses by frequency of administration, dialysis type and total patients (mITT population; N = 411)
| Average weekly doses (IU/kg) | ||||||
|---|---|---|---|---|---|---|
| Population by | Weeks 12–24 | Weeks 37–52 | ||||
| Frequency of administration | n (%) | Mean ± SD | Median (Range) | n (%) | Mean ± SD | Median (Range) |
| 3× per week | 158 (100.0) | 103.5 ± 88.0 | 77.9 (13.3–804.0) | 126 (79.8) | 114.4 ± 130.7 | 90.5 (0.0–1293.6) |
| 2× per week | 150 (100.0) | 76.9 ± 58.5 | 62.2 (11.5–417.5) | 131 (87.3) | 79.2 ± 68.6 | 62.01 (2.5–436.5) |
| 1× per week | 103 (100.0) | 65.9 ± 57.8 | 48.8 (2.3–335.0) | 88 (85.4) | 80.9 ± 96.8 | 47.5 (0.0–622.6) |
| Dialysis type | ||||||
| Predialysis | 32 (100.0) | 87.7 ± 73.5 | 56.0 (19.1–335.0) | 26 (81.2) | 122.6 ± 133.3 | 73.2 (14.9–622.6) |
| Haemodialysis | 288 (100.0) | 82.3 ± 57.9 | 66.5 (2.3–396.0) | 242 (84.0) | 90.5 ± 102.6 | 69.0 (0.0–1293.6) |
| Peritoneal dialysis | 91 (100.0) | 89.8 ± 107.3 | 60.4 (12.2–804.0) | 77 (84.6) | 88.8 ± 92.4 | 61.9 (4.4–436.5) |
| Total | 411 (100.0) | 84.4 ± 72.7 | 64.8 (2.3–804.0) | 345 (83.9) | 92.5 ± 103.1 | 66.0 (0.0–1293.6) |