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. 2009 Mar 17;10:113. doi: 10.1186/1471-2164-10-113

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Copyright © 2009 Slevin et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MMP-2 was expressed strongly in stroked regions: A, tissue from the contralateral hemisphere showed no observable staining (negatively stained blood vessels are marked with arrows; × 40). B, peri-infarcted stroked brain tissue showing microvessels stained positive for MMP-2 (I; × 40; arrows) and (ii) at higher magnification (× 100) and (iii) in stroke/infarcted tissue (× 100; arrows). C, shows positive staining of cells with the morphological appearance of astrocytes/glia staining for MMP-2 in infarcted tissue (× 100; arrows) and D, cytoplasmic staining of neurones in the same region (× 100; arrows). Ei-iii, double immunoflourescence showing co-localization of MMP-2 (red) and CD105 (green) in peri-infarcted stroke tissue (× 100; arrow; sections from I0715P were used).