Table 2.
Cases (%) | Controls (%) | OR (95%CI)a | |
---|---|---|---|
COMT Genotype* | 1212(100)† | 1683(100) | |
Val/Val | 271(22.4) | 400(23.8) | 1.00(Ref) |
Val/Met | 607(50.1) | 837(49.7) | 1.02(0.83, 1.24) |
Met/Met | 334(27.6) | 446(26.5) | 1.02(0.82, 1.28) |
Val/Val | 271(22.4) | 400(23.8) | 1.00(Ref) |
Val/Met + Met/Met | 941(77.6) | 1283(76.2) | 1.02(0.84, 1.23) |
| |||
COMT | MPO Genotype*¶ | 1175(100)† | 1631(100)† | |
Met158 Met | MPO T-764T | 204 (17.4) | 280 (17.2) | 1.00 (Ref) |
Met158 Met | MPO T-764C | 105 (8.9) | 141 (8.7) | 0.98 (0.71, 1.37) |
Met158 Met | MPO C-764C | 11 (0.9) | 13 (0.8) | 1.21 (0.51, 2.86) |
Met158 Val | MPO T-764T | 369 (31.4) | 500 (30.7) | 1.03 (0.81, 1.31) |
Met158 Val | MPO T-764C | 202 (17.2) | 266 (16.3) | 1.11 (0.84, 1.46) |
Met158 Val | MPO C-764C | 25 (2.1) | 39 (2.4) | 0.88 (0.51, 1.53) |
Val158 Val | MPO T-764T | 169 (14.4) | 252 (15.5) | 0.99 (0.74, 1.31) |
Val158 Val | MPO T-764C | 86 (7.3) | 123 (7.5) | 1.08 (0.76, 1.54) |
Val158 Val | MPO C-764C | 4 (0.3) | 17 (1.0) | 0.28 (0.08, 1.00) |
Unconditional logistic regression adjusted for the matching factors and BMI at age 18, weight gain since age 18, age at menarche, personal history of benign breast disease, first-degree family history of breast cancer, age at first birth/parity, age at menopause, and duration of postmenopausal hormone use.
Numbers do not add to the total number of women due to missing values in genotyping or covariates.
The sum of percentage does not add up to 100 due to rounding.
P-interaction = 0.57