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. 2009 Apr 3;15:654–661.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of rejection upon corneal allografts. A: The rejection kinetics of corneal transplantation in the DA-Lewis combination is shown. Sixteen Lewis rats served as recipients of DA allografts. The opacity grade 3 or 4 is defined as rejection onset. The rejection happened in all allografts from day 11 to day 14 with an MST of 13.1±0.3 days (n=16). Meanwhile, no rejection was observed in any of the isografts (n=6). B: The EC staining in a normal DA cornea is displayed. The cells were distributed regularly, and their nuclei exhibited similar shape (magnification 400X). C: The EC staining in rejected corneal allograft is shown. All ECs were lost except the remaining apoptotic cell (400X).