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. Author manuscript; available in PMC: 2009 Apr 3.
Published in final edited form as: J Invest Dermatol. 2000 Aug;115(2):234–244. doi: 10.1046/j.1523-1747.2000.00034.x

Table II.

Chemokine profiles in CXCR2+/+ and −/− micea

Day post-wounding MIP-2
 MIP-1α
 MCP-1
 IL-1β
+/+ −/− +/+ −/− +/+ −/− +/+ −/−
1 162 ± 36 142 ± 36 172 ± 94 273 ± 56 253 ± 41 356 ± 158 305 ± 77 340 ± 69
2 138 ± 19 192 ± 54 377 ± 50 393 ± 167 207 ± 24 219 ± 88 253 ± 31 118 ± 41*
3 150 ± 13 145 ± 23 273 ± 80 228 ± 66 209 ± 69 234 ± 75 283 ± 5 92 ± 13*
4 119 ± 12 99 ± 14 241 ± 83 107 ± 28 122 ± 12 150 ± 34 172 ± 36 106 ± 32
a

Cytokines and chemokine profiles in wound fluid as measured by the sandwich ELISA technique at four different time points. Values indicate mean ± SEM from three to four independent observations. Wounded skin samples were collected and tissue homogenates were made on days 1–4 postinjury. All tissue results are expressed as pg per mg total protein recovered after homogenization of 3 mm punch biopsy. The level of statistical significance of the comparison between wild-type and CXCR2−/− mice is indicated by the asterisk to denote p-values < 0.05 based upon the Student’s two-tailed t test and ANOVA.