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. 2000 Jan 4;97(1):250–255. doi: 10.1073/pnas.97.1.250

Table 3.

Rates and types of changes for nuclear poly(AT) and poly(GT) microsatellites

Microsatellite Rate of mutation to 5-FOAR (per cell division) Rate of changes in tract (per cell division)* Types of alterations
−2 0 +2 Other Total
(AT)16.5 5.1 (4.5–6.4)  × 10−5 1.3  × 10−5 1 1 23 1 26
2.7 (2.6–3.1)  × 10−5
3.9  × 10−5
(GT)16.5 4.0 (2.4–5.5)  × 10−5 1.2  × 10−5 4 0 24 1 29
2.4 (1.9–3.3)  × 10−5
3.2  × 10−5
*

These rates were determined by multiplying the average rate of mutation to 5-FOAR by the proportion of 5-FOAR derivatives that had altered tracts. Most of the 5-FOAR derivatives that did not have a tract alteration had lost the reporter gene as a consequence of mitotic recombination. 

In this class are two 5-FOAR strains in which the tract had gained more than five repeats.