Table 1. probability of the adequacy for each simulation (P(Co|C)) and associated P′ of four observed measures of genetic diversity.
Models | Number of sequences | Growth rate | Migration rate | Hap. number | Pairwise difference | Hapl. diversity | Nucl. diversity | P(Co|C) |
Model 1 | 12 | 0 | 1 | 0.143 | 0.152 | 0.286 | 0.141 | 0.1240 |
0 | 0 | 0.111 | 0.139 | 0.286 | 0.130 | 0.1205 | ||
1 | 1 | 0.112 | 0.118 | 0.231 | 0.110 | 0.0905 | ||
1 | 0 | 0.093 | 0.117 | 0.223 | 0.113 | 0.0830 | ||
9 | 0 | 1 | 0.144 | 0.114 | 0.952 | 0.110 | 0.1305 | |
0 | 0 | 0.139 | 0.117 | 0.943 | 0.114 | 0.1235 | ||
1 | 1 | 0.102 | 0.083 | 0.828 | 0.082 | 0.0875 | ||
1 | 0 | 0.084 | 0.077 | 0.808 | 0.074 | 0.0860 | ||
8 | 0 | 1 | 0.717 | 0.106 | 0.000 | 0.104 | 0.0030 | |
0 | 0 | 0.704 | 0.119 | 0.000 | 0.118 | 0.0025 | ||
1 | 1 | 0.485 | 0.077 | 0.000 | 0.076 | 0.0010 | ||
1 | 0 | 0.499 | 0.097 | 0.000 | 0.095 | 0.0025 | ||
7 | 0 | 1 | 0.363 | 0.097 | 0.000 | 0.098 | 0.0025 | |
0 | 0 | 0.414 | 0.101 | 0.000 | 0.101 | 0.0010 | ||
1 | 1 | 0.318 | 0.085 | 0.000 | 0.085 | 0.0005 | ||
1 | 0 | 0.294 | 0.076 | 0.000 | 0.076 | 0.0025 | ||
Model 2 | 12 | 0 | 1 | 0.144 | 0.154 | 0.350 | 0.147 | 0.1470 |
0 | 0 | 0.130 | 0.118 | 0.324 | 0.111 | 0.1140 | ||
1 | 1 | 0.174 | 0.227 | 0.400 | 0.220 | 0.2025 | ||
1 | 0 | 0.184 | 0.171 | 0.412 | 0.167 | 0.1790 | ||
9 | 0 | 1 | 0.138 | 0.104 | 0.910 | 0.102 | 0.1210 | |
0 | 0 | 0.108 | 0.049 | 0.929 | 0.046 | 0.0695 | ||
1 | 1 | 0.169 | 0.191 | 0.967 | 0.188 | 0.1895 | ||
1 | 0 | 0.151 | 0.122 | 0.958 | 0.118 | 0.1375 | ||
8 | 0 | 1 | 0.726 | 0.100 | 0.000 | 0.097 | 0.0005 | |
0 | 0 | 0.688 | 0.049 | 0.000 | 0.048 | 0.0020 | ||
1 | 1 | 0.667 | 0.167 | 0.000 | 0.161 | 0.0005 | ||
1 | 0 | 0.618 | 0.104 | 0.000 | 0.101 | 0.0015 | ||
7 | 0 | 1 | 0.453 | 0.099 | 0.000 | 0.100 | 0.0015 | |
0 | 0 | 0.432 | 0.045 | 0.000 | 0.047 | 0.0010 | ||
1 | 1 | 0.347 | 0.188 | 0.000 | 0.192 | 0.0050 | ||
1 | 0 | 0.344 | 0.105 | 0.000 | 0.107 | 0.0050 | ||
Model 3a | 12 | 0 | 1 | 0.146 | 0.141 | 0.272 | 0.138 | 0.1335 |
0 | 0 | 0.058 | 0.048 | 0.195 | 0.045 | 0.0420 | ||
1 | 1 | 0.226 | 0.293 | 0.445 | 0.285 | 0.2745 | ||
1 | 0 | 0.170 | 0.143 | 0.404 | 0.138 | 0.1505 | ||
9 | 0 | 1 | 0.108 | 0.075 | 0.966 | 0.073 | 0.0960 | |
0 | 0 | 0.075 | 0.024 | 0.915 | 0.022 | 0.0405 | ||
1 | 1 | 0.164 | 0.227 | 0.959 | 0.222 | 0.2170 | ||
1 | 0 | 0.136 | 0.098 | 0.929 | 0.094 | 0.1100 | ||
8 | 0 | 1 | 0.595 | 0.057 | 0.000 | 0.053 | 0.0025 | |
0 | 0 | 0.601 | 0.026 | 0.000 | 0.026 | 0.0020 | ||
1 | 1 | 0.603 | 0.220 | 0.000 | 0.214 | 0.0005 | ||
1 | 0 | 0.597 | 0.078 | 0.000 | 0.076 | 0.0005 | ||
7 | 0 | 1 | 0.391 | 0.063 | 0.000 | 0.064 | 0.0040 | |
0 | 0 | 0.361 | 0.027 | 0.000 | 0.027 | 0.0010 | ||
1 | 1 | 0.346 | 0.171 | 0.000 | 0.173 | 0.0015 | ||
1 | 0 | 0.314 | 0.058 | 0.000 | 0.058 | 0.0025 | ||
Model3b | 12 | 0 | 1 | 0.119 | 0.116 | 0.251 | 0.110 | 0.1030 |
0 | 0 | 0.099 | 0.074 | 0.254 | 0.067 | 0.0705 | ||
1 | 1 | 0.210 | 0.275 | 0.424 | 0.268 | 0.2480 | ||
1 | 0 | 0.160 | 0.154 | 0.399 | 0.141 | 0.1525 | ||
9 | 0 | 1 | 0.093 | 0.069 | 0.920 | 0.064 | 0.0825 | |
0 | 0 | 0.092 | 0.041 | 0.860 | 0.040 | 0.0570 | ||
1 | 1 | 0.173 | 0.221 | 0.898 | 0.217 | 0.2045 | ||
1 | 0 | 0.139 | 0.108 | 0.865 | 0.105 | 0.1240 | ||
8 | 0 | 1 | 0.578 | 0.062 | 0.000 | 0.060 | 0.0010 | |
0 | 0 | 0.546 | 0.021 | 0.000 | 0.020 | 0.0015 | ||
1 | 1 | 0.528 | 0.226 | 0.000 | 0.224 | 0.0005 | ||
1 | 0 | 0.470 | 0.069 | 0.000 | 0.068 | 0.0035 | ||
7 | 0 | 1 | 0.339 | 0.066 | 0.000 | 0.066 | 0.0005 | |
0 | 0 | 0.302 | 0.021 | 0.000 | 0.021 | 0.0020 | ||
1 | 1 | 0.271 | 0.168 | 0.000 | 0.169 | 0.0005 | ||
1 | 0 | 0.275 | 0.075 | 0.000 | 0.076 | 0.0020 | ||
Model 3c | 12 | 0 | 1 | 0.170 | 0.143 | 0.404 | 0.138 | 0.1505 |
0 | 0 | 0.094 | 0.079 | 0.299 | 0.076 | 0.0760 | ||
1 | 1 | 0.239 | 0.315 | 0.492 | 0.303 | 0.2900 | ||
1 | 0 | 0.302 | 0.460 | 0.627 | 0.445 | 0.4190 | ||
9 | 0 | 1 | 0.094 | 0.063 | 0.920 | 0.061 | 0.0840 | |
0 | 0 | 0.087 | 0.029 | 0.905 | 0.026 | 0.0410 | ||
1 | 1 | 0.177 | 0.232 | 0.964 | 0.226 | 0.2190 | ||
1 | 0 | 0.128 | 0.080 | 0.907 | 0.074 | 0.0935 | ||
8 | 0 | 1 | 0.590 | 0.063 | 0.000 | 0.062 | 0.0015 | |
0 | 0 | 0.638 | 0.033 | 0.000 | 0.033 | 0.0020 | ||
1 | 1 | 0.587 | 0.204 | 0.000 | 0.199 | 0.0005 | ||
1 | 0 | 0.585 | 0.088 | 0.000 | 0.083 | 0.0015 | ||
7 | 0 | 1 | 0.373 | 0.064 | 0.000 | 0.065 | 0.0040 | |
0 | 0 | 0.389 | 0.037 | 0.000 | 0.039 | 0.0010 | ||
1 | 1 | 0.335 | 0.154 | 0.000 | 0.157 | 0.0010 | ||
1 | 0 | 0.330 | 0.086 | 0.000 | 0.086 | 0.0025 | ||
Model 4 | 12 | 0 | 1 | 0.075 | 0.094 | 0.197 | 0.089 | 0.0710 |
0 | 0 | 0.030 | 0.040 | 0.094 | 0.037 | 0.0165 | ||
1 | 1 | 0.141 | 0.192 | 0.356 | 0.183 | 0.1690 | ||
1 | 0 | 0.049 | 0.052 | 0.141 | 0.049 | 0.0370 | ||
9 | 0 | 1 | 0.054 | 0.044 | 0.698 | 0.042 | 0.0490 | |
0 | 0 | 0.018 | 0.007 | 0.440 | 0.007 | 0.0115 | ||
1 | 1 | 0.134 | 0.185 | 0.860 | 0.177 | 0.1730 | ||
1 | 0 | 0.049 | 0.039 | 0.559 | 0.038 | 0.0450 | ||
8 | 0 | 1 | 0.398 | 0.038 | 0.000 | 0.037 | 0.0030 | |
0 | 0 | 0.218 | 0.010 | 0.000 | 0.009 | 0.0025 | ||
1 | 1 | 0.578 | 0.181 | 0.000 | 0.175 | 0.0005 | ||
1 | 0 | 0.299 | 0.029 | 0.000 | 0.027 | 0.0020 | ||
7 | 0 | 1 | 0.195 | 0.037 | 0.000 | 0.037 | 0.0010 | |
0 | 0 | 0.086 | 0.007 | 0.000 | 0.007 | 0.0015 | ||
1 | 1 | 0.250 | 0.153 | 0.000 | 0.154 | 0.0030 | ||
1 | 0 | 0.092 | 0.024 | 0.000 | 0.024 | 0.0020 |
Co = combined P-values for observed values.
C = distribution of combined P-values for simulated values .
growth rate ∶ 1 = 0.00016/0 = 0.
migration rate : 1 = 0.0002/0 = 0.