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. 2009 Mar;57(3):239–247. doi: 10.1369/jhc.2008.952200

Figure 2.

Figure 2

Contribution of CD138+ cells to the expression of fibronectin and collagens I and IV in patients with MM. (A,B) Mononuclear cells from BM needle aspirates from patients with low- (n=6), mid- (n=5), and high- (n=3) grade plasmacytosis were sorted into CD138+ and CD138− lymphocyte populations and subjected to real-time quantitative RT-PCR analysis for (A) fibronectin (p>0.05) and (B) collagen IV (p<0.001 for mid/high grade MM compared with low grade). Results presented as percent of GAPDH mRNA expression. (C) Genomic collagen I was amplified from the mononuclear cells from BM needle aspirates (n=3, only Patients 1 and 2 are shown).