. 2009 Mar;57(3):239–247. doi: 10.1369/jhc.2008.952200

Table 2.

Clinical parameters of the BM donors

Diagnosis	PC infiltration (%)	Age (yr)	Sex	Light chain	Isotype	M-protein (g/liter) (diagnosis/at 1 year)	Response^a (at 1 year)
Normal	<5	52	F	Polyclonal	Polyclonal	ND/ND	—
Normal	<5	64	F	Polyclonal	Polyclonal	ND/ND	—
Normal	<5	74	F	Polyclonal	Polyclonal	ND/ND	—
Normal	NA	53	F	Polyclonal	Polyclonal	ND/ND	—
Normal	5–10	68	M	Polyclonal	Polyclonal	ND/ND	—
MGUS	5–10	78	F	κ	IgG	5/7.2	MM^b^,^c
MGUS	<5	73	M	λ	IgG	ND/ND	—
MGUS	5–10	62	M	N/A	IgG	ND/ND	—
MGUS	<10	86	M	κ	IgG	ND/ND	—
MGUS	5–10	70	F	κ	IgG	ND/ND	—
MGUS	5	91	M	κ	IgA	ND/ND	—
MM	5–10	47	F	κ	IgG	39/4	VGPR^a^,^c
MM	NA	77	F	κ	Non-secretory	ND/ND	CR^a
MM	10–15	65	F	λ	IgG	18/16	Smoldering
MM	10–20	65	M	NA	N/A	ND/ND	CR^a
MM	10–20	65	F	λ	N/A	ND/ND	Smoldering
MM	40	60	M	λ	IgM	3/27	SD^a^,^c
MM	40	50	M	κ	IgG	54/88	SD^a^,^c
MM	40	59	M	κ	IgG	42/14	PR^a^,^c^,^d
MM	40–50	62	M	κ	IgG	63/41	MR^a^,^c
MM	50	71	M	λ	IgA	44/23	MR^a^,^c
MM	80	72	M	κ	IgG	53/25	PR^a^,^e
MM	80	74	M	λ	IgG	42/8	PR^a^,^e
MM	80–100	38	F	λ	IgG	55/15	PR^a^,^e
MM	100	59	M	λ	IgG	29/ND	CR^a^,^e
MM	100	66	M	λ	N/A	6/1.6	PR^a^,^e

Response categories based on the International Myeloma Working Group uniform response criteria (2006): CR, complete response (remission), no detectable M-protein, <5% PC in BM; VGPR, very good partial response, ≥90% reduction in M-protein; PR, partial response, ≥50% reduction in blood M-protein; MR, minimal response, ≥25% but <50% reduction in blood M-protein; SD, stable disease, increase in M-protein.

Patient was not on treatment before progression.

Patient on continued treatment at 1 year.

Patient deceased.

Patient not on treatment at 1 year.

BM, bone marrow; PC, plasma cells; MGUS, monoclonal gammopathy of undetermined significance; MM, multiple myeloma; NA, not available; ND, not detected.