Table 3.
IHC staining of phosphoproteins in human clinical tumor tissues
| Tumor type |
||||||
|---|---|---|---|---|---|---|
| Antibody | Fixative | Lung squamous cell carcinoma | Breast ductal carcinoma | Breast lobular carcinoma | Colon adenocarcinoma | Colon mucin-producing adenocarcinoma |
| pMET | STF | +++ | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pIGF-1R/IR | STF | +++ | ++ | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pEGFR | STF | + | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pHER2 | STF | + | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pHER3 | STF | ++ | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pHER4 | STF | +++ | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pAkt | STF | − | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pMAPK | STF | + | ++ | − | − | − |
| 10% formalin | + | + | − | − | − | |
| pTyr | STF | ++ | − | − | − | − |
| 10% formalin | − | − | − | − | − | |
| pp53 | STF | +++ | ++ | +++ | ++ | + |
| 10% formalin | ++ | − | +++ | − | − | |
STF, Streck’s tissue fixative.