Table 2.
Statistical tests of haplotype frequencies (two, one, or zero copies of the common haplotype) across groups.
| Comparison | n | χ2 | d.f. | P | Significant SNPsa |
|---|---|---|---|---|---|
| 5 group: HC v. Sz v. SzAf v. Bip v. MDD | 593 | 17.5 | 8 | 0.026 | rs7103411 |
| 4 group: HC v. Sz v. SzAf v. (Bip+MDD) | 593 | 15.5 | 6 | 0.017 | rs7103411 |
| 3 group: HC v. Sz v. (SzAf+Bip+MDD) | 593 | 13.2 | 4 | 0.010 | rs4923463, rs7103411 |
| 2 group: HC v. (SzAf+Bip+MDD) | 385 | 8.5 | 2 | 0.015 | all |
| 2 group: Sz v. (SzAf+Bip+MDD) | 373 | 9.5 | 2 | 0.008 | rs7103411 |
| 2 group: Sz v. SzAf | 268 | 9.2 | 2 | 0.009 | rs4923463, rs7103411 |
HC, healthy control; Sz, schizophrenia; SzAf, schizoaffective disorder; Bip, bipolar disorder; MDD, major depressive disorder.
a. Final column indicates individual single nucleotide polymorphisms (SNPs) that demonstrated nominally significant (P=0.05) genotypic effects for the given comparison.