Table 3.
Cox Proportional hazards model for the covariates contributing to racial variations in overall survival of African Americans, Hispanics and Asians compared to Caucasians with local/regional prostate cancer
| Variables in models | Hazard ratio (HR)and 95% Confidence Interval (CI) in African Americans, Hispanics and Asians compared to Caucasians* |
||
|---|---|---|---|
|
African Americans |
Hispanics |
Asians |
|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Model 1: Race only | 1.26 (1.21−1.32) | 0.83 (0.75−0.92) | 0.72 (0.66−0.79) |
| Model 2: Race + socio-demographics | 1.13 (1.08−1.18) | 0.82 (0.74−0.92) | 0.66 (0.60−0.72) |
| Model 3: Race + socio-demographics + tumor characteristics | 1.11 (1.06−1.16) | 0.81 (0.73−0.90) | 0.64 (0.58−0.70) |
| Model 4: Race + socio-demographics + tumor characteristics + ADT | 1.12 (1.07−1.17) | 0.81 (0.73− 0.90) | 0.64 (0.58−0.70) |
| Model 5: Race + socio-demographics + tumor characteristics + ADT+ chemotherapy | 1.12 (1.07−1.17) | 0.81 (0.73− 0.90) | 0.64 (0.58−0.70) |
| Model 6: Race + socio-demographics + tumor characteristics + ADT+ chemotherapy + primary therapies | 1.06 (1.01−1.10) | 0.79 (0.71−0.87) | 0.64 (0.58−0.70) |
| Model 7: Race + socio-demographics + tumor characteristics + ADT+ chemotherapy + primary therapies + comorbidities | 0.98 (0.94−1.03) | 0.77 (0.69−0.86) | 0.63 (0.58−0.69) |
Notes and abbreviation:
Multi-racial model for overall survival of older men treated for local/regional prostate cancer. ADT= Androgen deprivation therapy