Figure 8.

Schematic representations of the molecules that interact with ezrin in the elongated spermatid and with radixin in the developing Sertoli cell. (A) In the elongated spermatid, ezrin binds to actin filament in the cytoplasm and also binds directly or indirectly to CFTR, which interacts with aquaporin 7 (AQP7) in the plasma membrane. (B) In the developing Sertoli cell, radixin binds to actin filament and also directly or indirectly to microtubules in the cytoplasm. Radixin may also bind to an unidentified transmembrane protein.