Figure 2.

Apoptosis in MDA-MB231 monolayer cells subjected to Foscan-photodynamic treatment (PDT). (A) Paraffin sections were stained with standard coloration HES. Note specific morphological features of apoptosis such as condensed eosinophilic cytoplasm and clumped marginated chromatin (thin arrows) or apoptotic bodies (thick arrows). (B) Transmission electron microscopy. Ultrastructural study showed an MDA-MB231 cell with a nuclear marginated chromatin and an increase in the cytosol density typical of apoptosis.