Table 1.

Baseline parameter values used in simulating the spatio-temporal profiles of cells and oxygen in a system of βTC3 cells encapsulated in spherical calcium alginate/poly-l-lysine/alginate (APA) beads

Parameter		Value	Reference
Effective diffusivity	Deff	1.4 cm2/day	Tziampazis and Sambanis (1995), Mehmetoglu et al. (1996), Stabler (2004)
Maximum O2 consumption	νmax	2.88 mmloe/(day × 109 cells	Tziampazis and Sambanis (1995)
Monod parameter–O2	Km	0.01mM	Tziampazis and Sambanis (1995)
Maximum specific growth rate	μg, max	0.35 day−1	Monolayer growth rate (Stabler et al., 2001)
Maximum specific death rate	μd, max	1.4dat−1	Graeber et al. (1996)
Minimum specific death rate	μd, min	0.00273 day−1	Tziampazis et al. (unpublished)
Monod Kg		0.01mM	parameter–growth Tziampazis et al. (unpublished)
Monod Kd		0.001mM	parameter–death Tziampazis et al. (unpublished)
Maximum cell density	Xmax	9 × 108 cells/ml	Calculated based on a 10 μm diameter cell