Skip to main content
. Author manuscript; available in PMC: 2009 Apr 3.
Published in final edited form as: Mol Cell Neurosci. 2005 Sep;30(1):58–66. doi: 10.1016/j.mcn.2005.05.007

Fig. 6.

Fig. 6

Inhibition of p53 transcriptional activity reduces gp120 neuro-toxicity. The small molecule p53 inhibitor, pifithrin-α (PFT), reduces gp120-induced neuronal death (*P < 0.001 vs. gp120) (A). PFT pretreatment (100 nM) also reduces gp120-induced Apaf-1 up-regulation in neurons as determined by Western blot (B).