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PKA activation induces Kv4.2g redistribution in hippocampal neurons. A, Representative images show that AMPA (50 μm) or FSK (10 μm) treatment causes Kv4.2 redistribution from dendritic spines. B, Summary plot shows a significant decrease in the percentage of spines containing Kv4.2g after AMPA (n = 10 neurons, 1296 spines) or FSK (n = 19 neurons, 2372 spines) treatment relative to control (n = 18 neurons, 2163 spines). All data are mean ± SE. *p < 0.001.
