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. Author manuscript; available in PMC: 2010 Feb 27.
Published in final edited form as: Chem Biol. 2009 Feb 27;16(2):121–131. doi: 10.1016/j.chembiol.2009.01.012

Figure 4. The UBR box protein family.

Figure 4

(A) A schematic diagram of UBR box proteins. UBR, UBR box; RING, RING finger; CRD, cysteine rich domain; HECT, HECT domain; PHD, plant homeodomain finger; UAIN, UBR-specific autoinhibitory domain.

(B) A sequence alignment of the UBR boxes from four species. Shown are the ∼70 amino acid regions where conserved Cys and His residues are highlighted (cyan). m, Mus musculus; d, D. melanogaster; a, A. thaliana; sc, S. cerevisiae.