Impact of hSERT S438T on [3H]MADAM competition binding by
SERT inhibitors
The Ki values for SERT inhibitors were determined at
hSERT WT and hSERT S438T in a [3H]MADAM competition binding assay
as described under “Experimental Procedures.” Data represent mean
± S.E. from at least three independent experiments (number of
replicates are given in parentheses) each performed in duplicate. The number
of methyl groups on the aminopropyl chain of the inhibitors is indicated.