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. 2008 Aug 13;28(33):8178–8188. doi: 10.1523/JNEUROSCI.1944-08.2008

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Copyright © 2008 Society for Neuroscience 0270-6474/08/288178-11$15.00/0

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Figure 6. — Rap2V12 transgenic mice exhibit impaired spatial learning. A, Hidden-platform Morris water maze. Latency to find hidden platform is plotted for 2- to 4-month-old Rap2V12 or wild-type mice receiving four trials a day for 14 d (each daily block is average of 4 trials). *p < 0.05, repeated-measures two-way ANOVA. B, Probe trial. After 14 d training, the platform was removed. Fraction of time spent in each quadrant was measured. T, Target quadrant; O, opposite quadrant; L, left adjacent quadrant; R, right adjacent quadrant. Error bars indicate SEM.