Table 1.
Adverse effects of mesalamine and thiopurines in a cohort of IBD patients[18]
Event | Number | Percentage (%) |
Mesalamine (n = 44) | ||
Pulmonary dysfunction | 3 | 6.8 |
Pancreatitis | 1 | 2.2 |
Hemolytic anemia | 1 | 2.2 |
Intolerance to local drug vehicle | 1 | 2.2 |
Platelet reduction | 1 | 2.2 |
Diarrhea | 1 | 2.2 |
Total | 8 | 17.8 |
Thiopurines (n = 57) | ||
Leukopenia | 10 | 17.5 |
Hepatic damage | 5 | 8.77 |
Infection | 4 | 7.0 |
Pancreatitis | 4 | 7.0 |
Idiosyncracy | 2 | 3.50 |
Nausea | 1 | 1.75 |
Malignancy | 1 | 1.75 |
Total | 27 | 47 |