Table 3.
Distribution of genotypes for IL-1β (-511 and -31), IL-1RN and TNF-α in the control group and in patients with gastrointestinal pathologies n (%)
| Genotypes | Control | Gastritis | DU | GU | AC |
| n= 100 | n= 80 | n= 33 | n= 34 | n= 30 | |
| IL-1β-31 | |||||
| T/T | 9 | 3 (4) | 1 (3) | 2 (6) | 1 (4) |
| C/T | 23 | 21 (26) | 9 (27) | 7 (20) | 4 (13) |
| C/C | 68 | 56 (70) | 23 (70) | 25 (74) | 25 (83) |
| P value | NS | NS | NS | NS | |
| IL-1β-511 | |||||
| C/C | 31 | 26 (33) | 9 (27) | 10 (29) | 6 (20) |
| C/T | 46 | 34 (42) | 13 (39) | 14 (41) | 11 (37) |
| T/T | 23 | 20 (25) | 11 (34) | 10 (30) | 13 (43) |
| P value | NS | NS | NS | NS | |
| IL-1RN | |||||
| 1/1 | 58 | 41 (51) | 15 (46) | 11 (32) | 10 (33) |
| 1/2 | 36 | 34 (43) | 16 (49) | 21 (62) | 19 (63) |
| 2/2 | 6 | 5 (6) | 2 (6) | 2 (6) | 1 (4) |
| P value | NS | NS | 0.00 | 0.00 | |
| TNF-α | |||||
| G/G | 86 | 62 (77) | 23 (70) | 29 (85) | 24 (80) |
| G/A | 13 | 16 (20) | 8 (24) | 4 (12) | 5 (16) |
| A/A | 1 | 2 (3) | 2 (6) | 1 (3) | 1 (4) |
| P value | NS | NS | NS | NS |
DU: Duodenal ulcer; GU: Gastric ulcer; AC: Adenogastric carcinoma; G Test: Control versus disease; NS: Not significant.