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. 2009 Mar 28;15(12):1465–1471. doi: 10.3748/wjg.15.1465

Table 4.

Combined risk of polymorphism in the IL1-RN gene and IgG CagA antibody for development of gastric ulcers and adenogastric carcinoma

IL1-RN CagA Control GU ORa (95% IC) P AC ORb (95% IC) P
1/1 (-) 15 (24%) 2 (6%) Ref. - 1 (4%) Ref. -
2* carrier (-) 8 (13%) 2 (6%) 1.875c 0.983 1 (4%) 1.875c 0.735
1/1 (+) 21 (35%) 9 (27%) 3.214 (0.605-17.063) 0.289 8 (30%) 5.714 (0.644-50.648) 0.185
2* carrier (+) 17 (28%) 20 (61%) 8.823 (1.762-44.181) 0.008 19 (62%) 16.764 (1.997-140.707) 0.004
Total 61 33 29

GU: Gastric ulcer; AC: Adenogastric carcinoma.

a

Control x GU;

b

Control x AC;

c

The confidence interval was not calculated, since, n1p1q1 < 5 or n2p2q2 < 5.