Table 5.
Association of polymorphism for IL-RN gene and anti-CagA antibodies with histopathological findings from patients
IL1-RN | CagA |
DI |
OR (95% CI) | P |
NA |
OR (95% CI) | P |
Metaplasia |
OR (95% CI) | P | |||
1 | 2 and 3 | 1 | 2 and 3 | + | - | ||||||||
1/1 | (-) | 13 | 2 | - | - | 12 | 3 | - | - | 1 | 14 | - | - |
2* carrier | (-) | 9 | 1 | 0.722a | 0.706 | 8 | 2 | 1a | 0.609 | 2 | 8 | 3.5a | 0.706 |
1/1 | (+) | 24 | 34 | 9.2 00 (1.90-44.606) | 0.004 | 26 | 32 | 4.923 (1.254-19.314) | 0.032 | 17 | 41 | 5.804 (0.706-47.693) | 0.139 |
2* carrier | (+) | 20 | 63 | 20.475 (4.253-98.556) | 0.001 | 23 | 60 | 10.434 (2.695-40.388) | 0.003 | 35 | 58 | 8.448 (1.064-67.065) | 0.038 |
DI: Degree of inflammation; NA: Neutrophilic activity. Histopathological parameters: 1: Light; 2: Moderate; 3: Intense.
The confidence interval was not calculated, since, n1p1q1 < 5 or n2p2q2 < 5.