Fig. 4.
Common genetic variants account for transcript isoform variation of OAS1 between populations. Probesets PS3432457, PS3432458, PS3432462 and PS3432463 and PS3432463 of OAS1 were differentially spliced between the CEU and YRI samples. PS3432462 had a lower splicing index in the CEU samples. PS3432457 and PS3432458 had a lower splicing index in the YRI samples (Supplemental Table 1). The box plots show some local SNPs associated with the splicing index under an additive model. The red bar in PS3432463 indicates a probe potentially affected by two known SNPs (rs3435934 and rs45507596) in dbSNP v129. This probe was filtered before summarizing the probeset intensity
