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. Author manuscript; available in PMC: 2009 Apr 3.
Published in final edited form as: Hear Res. 2007 Jun 27;232(1-2):1–19. doi: 10.1016/j.heares.2007.06.011

Figure 5.

Figure 5

Low resolution images of explants treated with myosin disruption agents Y-27632 (A) or ML-9 (E) reveal hair bundle loss (small arrows). Explants treated with these myosin disruption agents plus gentamicin (B,F) show greater hair bundle loss compared to myosin disruption agent treatment only (A,E). High resolution imaging of explants treated with Y-27632 (C,D) or ML-9 (F,H) show a mix of closed scar formations (arrows), and partially-closed scar formations (arrowheads). Some closed scars appeared weakly-fluorescent and structurally disorganized (D,H arrow). Partially-closed scars have little fluorescence at the leading edges of newly-expanding supporting cell apical processes (G,H).