Table 2.

Hair bundle density (per 10,000 µm², +/− s.d.) after 24 hours explantation with various treatments.

Hair bundle Density (per 10,000 µm², +/− s.d.)
	Left		t-test vs left ACM	Right		t-test vs CL explantΦ	t-test vs right GT-only explant†
	density	+/−		density	+/−
in situ (n=3)	89.4	4.3	**	87.8	2.2	n.s.	-
24 hour explantation	Left saccule (control)Φ			Right saccule plus gentamicin
ACM (4)	81.4	4.4	-	73.6†	3.6	***	-
Incubation with cytoskeletal disruption agents
+ colchicine (3)	63.5	3.5	**	56.6	3.0	*	***
+ taxol (3)	80.4	6.6	n.s.	64.4	10.9	*	n.s.
+ ML-9 (4)	44.4	19.6	*	31.4	22.7	*	**
+ Y-27632 (2)‡	62.2	11.9	*	47.9	9.9	*	***
+ cytochalasin D (3)	76.5	4.6	n.s.	67.1	6.7	*	n.s.
+ latrunculin A (3)	84.0	3.1	n.s.	76.7	1.5	*	n.s.

^n.s.not statistically significantly different

^*p < 0.05

^**p < 0.01

^***p < 0.01

^CLcontra-lateral

^GTgentamicin

^‡Note, only 2 morphologically intact explants treated with Y-27632 used for statistical analysis and imaging.