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mtDNA copy number in polg-1(ok1548), HIS-72::mCherry mutants
| Developmental stages | HIS-72::mCherry (×104) | polg-1(ok1528), HIS-72::mCherry (×104) |
|---|---|---|
| D1 (n = 4) | 256.32 ± 33.78 | 19.66 ± 1.20*** |
| D8 (n = 4) | 760.11 ± 181.86 | 9.28 ± 0.49*** |
| D15 (n = 4) | 809.06 ± 148.44 | 5.72 ± 1.58*** |
Numbers represent absolute mtDNA levels/worm ± SEM. Level of statistical significance [***P<0.001, Student's t-test, (n = 4)]. mtDNA copy number was determined at day 1 (D1), day 8 (D8) and day 15 (D15) of adulthood.
