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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2008 Dec;67(12):1166–1186. doi: 10.1097/NEN.0b013e318190d6db

Figure 4.

Figure 4

Figure 4

Accumulation of delicate tubulovesicular elements in presynaptic axon terminals in aged SMG-CG. (A–C) Presynaptic nerve terminals show anastomosing tubulovesicular elements (arrows) in close apposition to the active zone and admixed with agranular synaptic vesicles. Magnification bars: A, 500 nm; B, 100 nm; C, 500 nm. (D, E) Intimate association of agranular and heterogeneous agranular elements with tubulovesicular elements. Magnification bars: D, E, 500 nm. (F) Tubulovesicles may form connections with the axolemma (arrow). Magnification bar: 500 nm. (G) Progressive enlargement of presynaptic nerve terminals is dominated by delicate tubulovesicular elements. Magnification bar: 500 nm. (H) Typical dystrophic axon (arrow) is large with compact tubulovesicular elements. Magnification bar: 2 μm.