Table 1.
Clinical Characteristics of Dippers and Non Dippers.*
| Clinical Characteristics | Dippers 34% (n=14) |
Non-dippers 66% (n=27) |
p value |
|---|---|---|---|
| Age (yr) | 70 ± 2 | 72 ± 2 | 0.526 |
| Gender (male/female) | 7 / 7 | 18 / 9 | 0.300 |
| Duration of disease (yr) | 5.9 ± 0.9 | 7.7 ± 1.1 | 0.536 |
| PMH of HTN (n=8) | 21 % (3) | 19 % (5) | 0.824 |
| BMI (Kg/m2) | 24 ± 1 | 25 ± 1 | 0.350 |
| Plasma Creatinine (mg/dL) | 1.06 ± 0.05 | 1.21 ± 0.08 | 0.454 |
| BP (mm Hg) and HR (bpm) monitoring | |||
| 8PM- 10PM (Baseline) | |||
| SBP | 182 ± 4 | 175 ± 3 | 0.215 |
| DBP | 93 ± 2 | 90 ± 2 | 0.434 |
| HR | 71 ± 2 | 67 ± 1 | 0.106 |
| 12AM-6AM (Sleeping period) | |||
| SBP | 147 ± 5 | 171 ± 4 | 0.001 |
| DBP | 81 ± 3 | 89 ± 2 | 0.039 |
| HR | 68 ± 2 | 65 ± 1 | 0.274 |
| 8AM | |||
| SBP | 163 ± 6 | 175 ± 5 | 0.161 |
| DBP | 88 ± 3 | 92 ± 3 | 0.395 |
| HR | 72 ± 3 | 68 ± 2 | 0.152 |
| Normalization of Nighttime SBP† | 50 % (7) | 15 % (4) | 0.016 |
*
Values expressed as mean ± SEM. Number of patients is in parentheses.PMH, past medical history in years; HTN, essential hypertension; BMI, body mass index; BP, blood pressure; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure.
†
Percentage of patients with a SBP, averaged between 12 AM and 6 AM, of <150 mm Hg.