Table III.
Plasma cytokine concentrations following LPS stimulation of whole blood in vitro according to the FyX polymorphism in Caucasiansa
| FyX Genotype in Caucasians |
||||
|---|---|---|---|---|
| Cytokine | TT (0) | CT (6) | CC (289) | p |
| CXCL8 | NA | 3770 ± 821 | 3157 ± 186 | 0.2518 |
| IL-1β | NA | 7587 ± 1412 | 7705 ± 453 | 0.8656 |
| TNF-α | NA | 4482 ± 1048 | 5298 ± 312 | 0.2788 |
| CCL2 | NA | 2136 ± 138 | 1796 ± 106 | 0.0676 |
a
CXCL8, IL-1β, TNF-α, and CCL2 concentrations in picograms per monocyte count (×103/μl) and their corresponding SEM are depicted in columns according to genotype. The numbers in parentheses in each genotype column represent the number of individuals tested. NA, Not available. Statistical comparisons made between genotypes for each variable cytokine are depicted in the far right-hand column. Data were analyzed by rank sum Mann-Whitney U test and p < 0.05 defined as significant.