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. Author manuscript; available in PMC: 2009 Apr 5.
Published in final edited form as: Nature. 2005 Mar 17;434(7031):325–337. doi: 10.1038/nature03440

Figure 4.

Figure 4

Conservation of the X chromosome in eutherian mammals. Plot of BLASTZ sequence alignments between the human X chromosome and the mouse (red) and rat (blue) X chromosomes. The rodent chromosomes are oriented with their centromeres pointing downwards. Regions indicated with arrows are long, highly similar repeats in the mouse sequence that are absent from the human and rat sequences. These repeats were apparently collapsed in an earlier analysed version of the mouse sequence, which also had a large inversion with respect to the mouse assembly used here (NCBI32)66. The NCBI32 assembly has a gap from 0-3 Mb, which explains the absence of homology to the human X sequence in this part of the plot. The open horizontal bar shows the terminal section of human Xp, which is not conserved on the rodent X chromosomes.