Table 3.
Rho subfamilies in Vertebrates
| Sub-family | Homo sapiens | Monodelphis domestica | Gallus gallus | Xenopus tropicalis | Xenopus laevis | Brachydanio rerio | Tatifugu rubripes | Tetraodon nigroviridis |
|---|---|---|---|---|---|---|---|---|
| Cdc42a | HsCdc42 | MdCdc42a | GgCdc42 | XtCdc42 | XlCdc42 | BrCdc42a | FrCdc42a1 | TnCdc42a1 |
| MdCdc42b | BrCdc42b | FrCdc42a2 | TnCdc42a2 | |||||
| MdCdc42c | BrCdc42c | FrCdc42b | TnCdc42b | |||||
| HsRhoJ | MdRhoJ | GgRhoJ | XtRhoJ | XlRhoJ | BrRhoJ | absent | Absent | |
| HsRhoQ | MdRhoQ | GgRhoQ | XtRhoQ | not found | BrRhoQ | FrRhoQ | TnRhoQ | |
| Rac | HsRac1 | MdRac1 | GgRac1 | XtRac1 | XlRac1a | BrRac1a | FrRac1a | TnRac1a |
| HsRac1bb | MdRac1bb | GgRac1bb | XlRac1b | BrRac1b | FrRac1b | TnRac1b | ||
| XlRac1c1 | TnRac1b1 | |||||||
| XlRac1c2 | TnRac1b2 | |||||||
| HsRac2 | MdRac2 | GgRac2 | XtRac2 | XlRac2 | BrRac2 | FrRac2 | TnRac2 | |
| HsRac3 | MdRac3 | GgRac3 | XtRac3 | not found | BrRac3 | FrRac3 | Absent | |
| HsRhoG | MdRhoG | GgRhoG | XtRhoG1 | XlRhoG1 | BrRhoG1 | FrRhoG1 | TnRhoG1 | |
| MdRhoG1 | XtRhoG2a | BrRhoG2a | FrRhoG2 | TnRhoG2 | ||||
| MdRhoG2 | XtRhoG2b | BrRhoG2b | ||||||
| BrRhoG3 | ||||||||
| BrRhoG3p | ||||||||
| BrRhoG4 | ||||||||
| RhoUV | HsRhoU | MdRhoU | GgRhoU | XtRhoU | XlRhoU1 | BrRhoU1 | FrRhoU1 | TnRhoU1 |
| XlRhoU2a | BrRhoU2 | FrRhoU2 | TnRhoU2 | |||||
| XlRhoU2b | BrRhoU3 | FrRhoU3 | ||||||
| HsRhoV | MdRhoV | GgRhoV | XtRhoV | XlRhoVl | BrRhoV | FrRhoV1 | TnRhoV1 | |
| XlRhoV2 | FrRhoV2 | TnRhoV2 | ||||||
| Rho | HsRhoA | MdRhoA | GgRhoA | XtRhoA1 | XlRhoA1a | BrRhoA1 | FrRhoA1a | TnRhoA1a |
| MdRhoAps1 | GgRhoAp | XtRhoA2 | XlRhoA1b | BrRhoA2 | FrRhoA1b | TnRhoA1b | ||
| MdRhoAps2 | XlRhoA1c | BrRhoACa | FrRhoAC | TnRhoAC | ||||
| XlRhoA2 | BrRhoACb | |||||||
| HsRhoB | MdRhoB | GgRhoB | XtRhoB | XlRhoB1 | BrRhoB | FrRhoB | TnRhoB | |
| XlRhoB2 | ||||||||
| HsRhoC | MdRhoC | GgRhoC | XtRhoC | XlRhoC1 | BrRhoC1a | FrRhoC1 | TnRhoC1a | |
| XlRhoC2 | BrRhoC1b | FrRhoC2 | TnRhoC1b | |||||
| BrRhoC2 | TnRhoC2 | |||||||
| RhoBTB | HsRhoBTB1 | MdRhoBTB1 | GgRhoBTB1 | XtRhoBTB1 | XlRhoBTB1 | BrRhoBTB1 | absent | Absent |
| HsRhoBTB2 | MdRhoBTB2 | GgRhoBTB2 | XtRhoBTB2 | not found | BrRhoBTB2a | FrRhoBTB2a | TnRhoBTB2a | |
| BrRhoBTB2b | ||||||||
| BrRhoBTB2c | FrRhoBTB2c | TnRhoBTB2c | ||||||
| RhoDF | HsRhoD | MdRhoD | absent | absent | not found | absent | absent | Absent |
| HsRhoF | MdRhoF | GgRhoF | XtRHoF | XlRhoF1 | BrRhoF | FrRhoF | TnRhoF | |
| XlRhoF2 | ||||||||
| RhoH | HsRhoH | MdRhoH | GgRhoH | XtRhoH | not found | BrRhoH | FrRhoH | TnRhoH |
| Rnd | HsRnd1 | MdRnd1 | absent | XtRnd1 | XlRnd1a | BrRnd1a | FrRnd1a | TnRnd1 |
| XlRnd1b | BrRnd1b | FrRnd1b | ||||||
| HsRnd2 | MdRnd2 | GgRnd2 | absent | not found | BrRnd2 | FrRnd2a | TnRnd2a | |
| FrRnd2b | TnRnd2b | |||||||
| HsRnd3 | MdRnd3 | GgRnd3 | XtRnd3 | XlRnd3a | BrRnd3a | FrRnd3 | TnRnd3 | |
| XlRnd3b | BrRnd3b | |||||||
a
Notes Vertebrate Cdc42 members have two isoforms generated by differential splicing (see Table S4)
b
Isoform from the same locus as Rac1