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. 1988 Jun;26(6):1198–1201. doi: 10.1128/jcm.26.6.1198-1201.1988

Distinction of species and strains of mycoplasmas (mollicutes) by genomic DNA fingerprints with an rRNA gene probe.

D Yogev 1, D Halachmi 1, G E Kenny 1, S Razin 1
PMCID: PMC266561  PMID: 3384931

Abstract

Genomic fingerprints of Acholeplasma laidlawii, Mycoplasma hominis, and Mycoplasma pneumoniae strains were obtained by Southern blot hybridization of the digested mycoplasmal DNAs with an rRNA gene probe. The hybridization patterns revealed genotypic heterogeneity among A. laidlawii and M. hominis strains and a remarkable degree of homogeneity among M. pneumoniae strains isolated from pneumonia patients during a 10-year period. Genomic fingerprints with the rRNA gene probe can thus serve as indicators of intraspecies genetic homogeneity or heterogeneity and can provide a new, sensitive tool for strain identification with a potential for application in epidemiology.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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