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. 2009 Jan;155(1):88–95. doi: 10.1111/j.1365-2249.2008.03805.x

Fig. 6.

Fig. 6

Immunohistochemical localization of inducible nitric oxide synthase (iNOS) expression in colonic tissues of Trichinella spiralis antigen-treated and phosphate-buffered saline (PBS)-treated mice following dinitrobenzenesulphonic acid (DNBS) administration. Mice were treated with T. spiralis antigen (100 µg in 30 µl PBS) or with PBS submucosally in the rectum 5 days before the induction of colitis by DNBS. Colitis was induced by intracolonic administration of DNBS (5 mg) and iNOS expression was investigated by immunohistochemistry on day 3 post-DNBS. (a) iNOS-positive area. Data are expressed as the percentages of the positive staining areas of the total area. (b) iNOS immunostaining of colon tissue of PBS-treated mice in DNBS-induced colitis. (c) iNOS immunostaining of colon tissue of T. spiralis antigen-treated mice in DNBS-induced colitis. *iNOS-positive areas were significantly lower in T. spiralis antigen treated mice after DNBS compared with those in PBS-treated mice after DNBS.