Table 2.

Forestomach Squamous Epithelial Hyperplasia in Rats

	Dose (mg/kg) (AAC, AAL, ACR)	Allyl Acetate	Allyl Alcohol	Acrolein
Male
	0	0/10	0/10	0/10
	6, 1.5, 0.75	2/10 (1.0)	0/10	0/10
	12, 3, 1.25	6/10**(1.3)	0/10	0/10
	25, 6, 2.5	5/10*(1.8)	5/10*(1.0)	3/10(1.0)
	50, 12, 5	10/10**(2.0)	7/10**(1.0)	8/10**(1.0)
	100, 25, 10	4/10*(1.8)	6/10**(1.0)	9/10**(1.6)
Female
	0	0/10	0/10	0/10
	6, 1.5, 0.75	1/10(1.0)	0/10	0/10
	12, 3, 1.25	3/10(1.3)	1/10(1.0)	3/10(1.0)
	25, 6, 2.5	9/10**(1.2)	4/10*(1.0)	5/10*(1.0)
	50, 12, 5	7/10**(1.3)	9/10**(1.0)	8/10**(1.0)
	100, 25, 10	1/10(2.0)	8/10**(1.0)	9/10**(1.6)

^*Significantly different (P ≤ 0.05) from the vehicle control group by Fischer exact test

^**P ≤ 0.01