Table 4.
Survivala | Final body weightb | ||||||
---|---|---|---|---|---|---|---|
Dose (mg/kg) (AAC, AAL, ACR) |
Allyl Acetate |
Allyl Alcohol |
Acrolein | Allyl Acetate |
Allyl Alcohol |
Acrolein | |
Male | |||||||
0 | 9/10 | 10/10 | 10/10 | 36.3 ± 1.1 | 40.9 ± 1.1 | 35.6 ± 1.2 | |
8, 3, 1.25 | 7/10 | 10/10 | 9/10 | 38.1 ± 0.8 | 39.5 ± 1.2 | 36.1 ± 1.0 | |
16, 6, 2.5 | 10/10 | 10/10 | 10/10 | 36.6 ± 0.8 | 40.3 ± 0.9 | 37.7 ± 1.0 | |
32, 12, 5 | 9/10 | 10/10 | 9/10 | 36.8 ± 0.8 | 39.4 ± 1.0 | 36.5 ± 0.5 | |
62.5, 25, 10 | 2/10 | 10/10 | 9/10 | 36.2 ± 0.9 | 39.1 ± 1.0 | 34.3 ± 1.0 | |
125, 50, 20 | 0/10 | 10/10 | 0/10 | ----- | 37.9 ± 0.5 | ----- | |
Female | |||||||
0 | 9/10 | 10/10 | 9/10 | 30.7 ± 0.6 | 31.7 ± 1.2 | 29.8 ± 0.8 | |
8, 3, 1.25 | 8/10 | 10/10 | 10/10 | 31.9 ± 0.4 | 33.0 ± 1.3 | 33.6 ± 1.6 | |
16, 6, 2.5 | 6/10 | 10/10 | 10/10 | 32.7 ± 1.7 | 34.8 ± 1.5 | 31.5 ± 1.3 | |
32, 12, 5 | 7/10 | 10/10 | 9/10 | 31.3 ± 1.1 | 33.9 ± 1.0 | 27.1 ± 0.6 | |
62.5, 25, 10 | 6/10 | 10/10 | 8/10 | 29.7 ± 0.9 | 32.5 ± 1.3 | 28.5 ± 0.6 | |
125, 50, 20 | 0/10 | 9/10 | 0/10 | ----- | 31.4 ± 1.1 | ----- |
Number of animals surviving at 14 weeks/number initially in group
Weights in grams are given as mean ± standard error