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. Author manuscript; available in PMC: 2009 Nov 21.
Published in final edited form as: Toxicology. 2008 Sep 4;253(1-3):79–88. doi: 10.1016/j.tox.2008.08.014

Table 6.

Cytoplasmic vacuolization of hepatocytes in mice

Dose
(mg/kg)
(AAC, AAL, ACR)
Allyl
Acetate
Allyl
Alcohol
Acrolein

Male
0 0/10 0/10 0/10
8, 3, 1.25 0/10 0/10 0/10
16, 6, 2.5 0/10 0/10 0/10
32, 12, 5 0/10 0/10 0/10
62.5, 25, 10 6/10**(1.0) 2/10(1.0) 0/10
125, 50, 20 0/10 10/10**(1.0) 0/10
Female
0 0/10 1/10(1.0) 0/10
8, 3, 1.25 0/10 1/10(1.0) 0/10
16, 6, 2.5 0/10 1/10(1.0) 0/10
32, 12, 5 3/10(1.0) 5/10(1.0) 0/10
62.5, 25, 10 4/10*(1.3) 8/10**(1.0) 0/10
125, 50, 20 0/10 9/10(1.2) 0/10
*

Significantly different (P ≤ 0.05) from the vehicle control group by Fischer exact test

**

P ≤ 0.01