Patients | Interventions | Outcomes | |
---|---|---|---|
Meconium aspiration | Preterm or term infants born through MSAF | (a) perineal suction vs. no suction | Mortality, morbidity, MAS, pneumothorax, HIE, intubation complications |
(b) endotracheal suction vs. no suction | |||
Air vs. oxygen | Asphyxiated preterm or term neonates | Comparison of air vs. oxygen | Mortality, morbidity, neurodevelopmental sequelae |
Sodium bicarbonate | Preterm or term infants | Use of any dose/rate of sodium bicarbonate | Mortality, morbidity, neurodevelopmental disability |
MSAF: meconium-stained amniotic fluid; MAS: meconium aspiration syndrome; HIE: hypoxic ischaemic encephalopathy.