Figure 2.
Leishmania-induced IL-12p40 inhibition is independent of species and strain. RAW264.7 cells stably transfected with human IL-12p40-LUC construct were infected with different L. donovani (A) or L. major (B) substrains and treated with 100 U/ml IFN-γ plus 1 μg/ml LPS. Samples were run in triplicate and mean relative luciferase units ± standard deviation is reported. * Infected values were significantly different from uninfected, stimulated controls (P < 0.05). † Uninfected, stimulated values were different from uninfected, untreated controls (P < 0.05). In each case 1 representative of 2 independent experiments is shown.
