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. Author manuscript; available in PMC: 2009 Apr 6.
Published in final edited form as: J Parasitol. 2008 Feb;94(1):84–93. doi: 10.1645/GE-1153.1

Figure 5.

Figure 5

Inhibition of IL-12p40Luc by Leishmania is not dependent on LPG, PG, or GP63. RAW264.7 cells stably transfected with human IL-12p40-LUC construct were infected with Leishmania for 16 hr followed by 8 hr of LPS (1 μg/ml) stimulation. (A) Leishmania donovani wild-type, LPG-deficient, and PG-deficient mutants. (B) Leishmania mexicana wild-type and GP63-deficient mutant. Samples were run in triplicate and mean relative luciferase units ± standard deviation is reported. * Infected values were significantly different from uninfected, stimulated controls (P < 0.05). † Uninfected, stimulated values were different from uninfected, untreated controls (P < 0.05). One representative of 2 independent experiments is shown.