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. Author manuscript; available in PMC: 2010 Feb 24.
Published in final edited form as: ACS Nano. 2009 Feb 24;3(2):307–316. doi: 10.1021/nn800551s

Figure 1. Nanotube Based Delivery System.

Figure 1

(A) Illustration of chemical reactions used to attach EGF, cisplatin and Qdots onto carboxylated SWNTs (in red) using EDC as the coupling agent. (B) Schematic showing SWNT bundles bioconjugated with EGF and cisplatin targeting the cell surface receptor EGFR on a single HNSCC cell. Transmission electron micrographs of (c) oxidized SWNT bundles with arrows showing a single SWNT (d) SWNT-Qdot-EGF bioconjugate bundle (e) STEM image of SWNT bundle showing cisplatin as the bright spots. (scale bar = 10 nm)