Table 3.
Evaluation of plasma circulatory markers in Chlamydia pneumoniae IgA positive coronary artery disease patients and controls.
| Plasma circulatory markers | CAD patients | P-value | Controls | P-value | ||
|---|---|---|---|---|---|---|
| IgA (+ve) (n = 155) | IgA (−ve) (n = 37) | IgA (+ve) (n = 77) | IgA (−ve) (n = 115) | |||
| mean ± SD | mean ± SD | mean ± SD | mean ± SD | |||
| IL-4 (pg/mL) | 1.31 ± 0.13 | 1.17 ± 0.12 | .007* | 1.06 ± 0.08 | 0.92 ± 0.08 | <.001* |
| IL-8 (pg/mL) | 3.41 ± 0.31 | 2.76 ± 0.26 | .015* | 2.46 ± 0.23 | 2.31 ± 0.21 | .444 |
| IL-10 (pg/mL) | 1.82 ± 0.11 | 1.86 ± 0.11 | <.001* | 1.95 ± 0.14 | 1.96 ± 0.15 | .879 |
| IL-13 (pg/mL) | 4.84 ± 0.41 | 4.70 ± 0.42 | .918 | 4.34 ± 0.36 | 4.20 ± 0.40 | .773 |
| IFN-λ (pg/mL) | 1.57 ± 0.14 | 1.65 ± 0.12 | <.001* | 1.54 ± 0.14 | 1.56 ± 0.13 | .006* |
| ICAM-1 (ng/mL) | 14.54 ± 1.21 | 13.75 ± 1.24 | .048* | 13.16 ± 1.10 | 13.10 ± 1.09 | .528 |
| VCAM-1 (ng/mL) | 74.33 ± 6.27 | 72.21 ± 6.15 | .454 | 54.39 ± 4.76 | 54.10 ± 4.39 | .564 |
CAD: coronary artery disease; *: significant; SD: standard deviation; IL: interleukin; ng: nanogram; pg: pikogram; mL: mililiter; IFN: interferon; ICAM: Intercellular adhesion molecule; VCAM: vascular adhesion molecule; IgA: immunoglobulin A; +ve: positive; −ve: negative.