Table 4.
Evaluation of plasma circulatory markers in high-sensitive C-reactive protein positive coronary artery disease patients and controls.
| Plasma circulatory markers | CAD patients | P-value | Controls | P-value | ||
|---|---|---|---|---|---|---|
| hsCRP (+ve) (n = 116) | hsCRP (−ve) (n = 76) | hsCRP (+ve) (n = 60) | hsCRP (−ve) (n = 132) | |||
| mean ± SD | mean ± SD | mean ± SD | mean ± SD | |||
| IL-4 (pg/mL) | 1.31 ± 0.12 | 1.26 ± 0.11 | .719 | 1.00 ± 0.13 | 0.96 ± 0.12 | .090 |
| IL-8 (pg/mL) | 3.32 ± 0.31 | 3.20 ± 0.26 | .573 | 2.53 ± 0.21 | 2.29 ± 0.18 | .207 |
| IL-10 (pg/mL) | 1.82 ± 0.13 | 1.85 ± 0.14 | <.001* | 1.94 ± 0.15 | 1.96 ± 0.24 | <.001* |
| IL-13 (pg/mL) | 4.86 ± 0.30 | 4.74 ± 0.31 | .118 | 4.30 ± 0.33 | 4.23 ± 0.30 | .668 |
| IFN-λ (pg/mL) | 1.57 ± 0.12 | 1.59 ± 0.13 | <.001* | 1.54 ± 0.19 | 1.56 ± 0.17 | <.001* |
| ICAM-1 (ng/mL) | 14.53 ± 1.07 | 14.16 ± 1.17 | .563 | 13.25 ± 1.13 | 13.06 ± 1.09 | .330 |
| VCAM-1 (ng/mL) | 74.20 ± 7.21 | 73.47 ± 6.91 | .658 | 54.60 ± 4.92 | 54.10 ± 4.39 | .874 |
CAD: coronary artery disease; *: significant; SD: standard deviation; IL: interleukin; ng: nanogram; pg: pikogram; mL: mililiter; IFN: interferon; ICAM: intercellular adhesion molecule; VCAM: vascular adhesion molecule; hsCRP: high-sensitive C-reactive protein; +ve: positive; −ve: negative.