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Primary cultures of wild-type and Cav-1−/− mammary stromal fibroblasts. Phase contrast images at the same magnification are shown. MSFs spread out and are enlongated, as expected. Mammary epithelia are shown for comparison. Note that the mammary epithelial cells form a densely packed monolayer, with a characteristic “cobble-stone” appearance. WT, wild-type; KO, Cav-1−/−.
